UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________

SCHEDULE 13G

Under the Securities Exchange Act of 1934
Amendment No. 1

Advanced Accelerator Applications S.A.
(Name of Issuer)

Ordinary Shares, par value €0.10 per share
(Title of Class of Securities)

00790T100*
(CUSIP Number)

(Date of Event which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

*       This CUSIP number is assigned to the Issuer’s American Depositary Shares, each representing two (2) Ordinary Shares.

(1) Based on 87,952,657 ordinary shares outstanding as of December 31, 2016.

(1) Based on 87,952,657 ordinary shares outstanding as of December 31, 2016.

(1) Based on 87,952,657 ordinary shares outstanding as of December 31, 2016.

Item 1(a). Name of Issuer:

Advanced Accelerator Applications S.A. (“AAA”)

Item 1(b). Address of Issuer’s Principal Executive Offices:

20 rue Diesel, 01630 Saint Genis Pouilly, France

Item 2(a). Name of Person Filing:

This Schedule 13G is jointly filed by Andrea Ruben Osvaldo Levi, PARABENSA S.R.L. and DAL 1802 ECSAT S.R.L.

Item 2(b). Address of Principal Business Office or, if None, Residence:

The principal business address of Andrea Ruben Osvaldo Levi is: Corso D’Azeglio 21, Torino 10126, Italy.

The principal business address of PARABENSA S.R.L. is: Corso D’Azeglio 21, Torino 10126, Italy.

The principal business address of DAL 1802 ECSAT S.R.L. is: Via Principe Amedeo 11, Torino 10123, Italy.

Item 2(c). Citizenship:

Mr. Levi is an Italian citizen.

PARABENSA S.R.L. is a limited liability company (Società a Responsabilità Limitada) organized under the laws of Italy.

DAL 1802 ECSAT S.R.L. is a limited liability company (Società a Responsabilità Limitada) organized under the laws of Italy.

Item 2(d). Title of Class of Securities:

Ordinary Shares, par value €0.10 per share (the “Ordinary Shares”).

Item 2(e). CUSIP Number:

00790T100. This CUSIP number is assigned to the Issuer’s American Depositary Shares, each representing two (2) Ordinary Shares.

Item 3. If this Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a:

Not Applicable.

Item 4. Ownership.

(a)       Amount beneficially owned:

Mr. Levi directly owns 3,426,000 Ordinary Shares. Mr. Levi may also be deemed to have shared voting power and shared power to dispose of an additional 1,830,000 Ordinary Shares. In total, Mr. Levi may be deemed to beneficially own 5,256,000 Ordinary Shares.

PARABENSA S.R.L. directly owns 1,000,000 Ordinary Shares.

DAL 1802 ECSAT S.R.L. directly owns 830,000 Ordinary Shares.

(b)       Percent of class:

Mr. Levi may be deemed to beneficially own 6.0% of the outstanding Ordinary Shares of AAA, based on the 87,952,657 Ordinary Shares outstanding as of December 31, 2016.

PARABENSA S.R.L. owns 1.1% of the outstanding Ordinary Shares of AAA, based on the 87,952,657 Ordinary Shares outstanding as of December 31, 2016.

DAL 1802 ECSAT S.R.L. owns 0.9% of the outstanding Ordinary Shares of AAA, based on the 87,952,657 Ordinary Shares outstanding as of December 31, 2016.

Mr. Levi has sole voting power of 3,426,000 Ordinary Shares.

PARABENSA S.R.L. has sole voting power of 0 Ordinary Shares.

DAL 1802 ECSAT S.R.L. has sole voting power of 0 Ordinary Shares.

Mr. Levi has shared voting power of (i) 1,000,000 Ordinary Shares through PARABENSA S.R.L., in which he has a 95% ownership stake and is the sole director, and (ii) 830,000 Ordinary Shares through DAL 1802 ECSAT S.R.L., in which he has a 99.96% ownership stake and is one of three directors. In total, Mr. Levi may be deemed to have shared voting power of 1,830,000 Ordinary Shares.

PARABENSA S.R.L. has shared voting power of 1,000,000 Ordinary Shares.

DAL 1802 ECSAT S.R.L. has shared voting power of 830,000 Ordinary Shares.

Mr. Levi has sole power to dispose of 3,426,000 Ordinary Shares.

PARABENSA S.R.L. has sole power to dispose of 0 Ordinary Shares.

DAL 1802 ECSAT S.R.L. has sole power to dispose of 0 Ordinary Shares.

Mr. Levi has shared power to dispose of (i) 1,000,000 Ordinary Shares through PARABENSA S.R.L., in which he has a 95% ownership stake and is the sole director, and (ii) 830,000 Ordinary Shares through DAL 1802 ECSAT S.R.L., in which he has a 99.96% ownership stake and is one of three directors. In total, Mr. Levi may be deemed to have shared power to dispose of 1,830,000 Ordinary Shares.

PARABENSA S.R.L. has shared voting power of 1,000,000 Ordinary Shares.

DAL 1802 ECSAT S.R.L. has shared voting power of 830,000 Ordinary Shares.

Item 5. Ownership of Five Percent or Less of a Class.

Not Applicable.

Item 6. Ownership of More than Five Percent on Behalf of Another Person.

None.

Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company.

Not Applicable.

Item 8. Identification and Classification of Members of the Group.

See Exhibit A to the Schedule 13G filed on February 10, 2016.

Item 9. Notice of Dissolution of Group.

Not Applicable.

Item 10. Certifications.

Not Applicable.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: February 8, 2017